{"id":38069,"date":"2024-12-18T10:13:17","date_gmt":"2024-12-18T03:13:17","guid":{"rendered":"https:\/\/postgraduate.md.kku.ac.th\/?p=38069"},"modified":"2024-12-18T10:13:18","modified_gmt":"2024-12-18T03:13:18","slug":"assoc-prof-laddawan-senggunprai","status":"publish","type":"post","link":"https:\/\/postgraduate.md.kku.ac.th\/?p=38069","title":{"rendered":"Assoc. Prof.Laddawan Senggunprai"},"content":{"rendered":"<div class=\"gb-container gb-container-b02d4dd0\">\n<div class=\"gb-container gb-container-a3a51e82\">\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:80%\">\n<figure class=\"wp-block-image size-full is-resized\" id=\"wp-block-themeisle-blocks-image-439d771d\"><img fetchpriority=\"high\" decoding=\"async\" width=\"200\" height=\"250\" src=\"https:\/\/postgraduate.md.kku.ac.th\/wp-content\/uploads\/2024\/12\/3.png\" alt=\"\" class=\"wp-image-38070\" style=\"width:auto;height:200px\"\/><\/figure>\n\n\n\n<p class=\"gb-headline gb-headline-5b43e6fe gb-headline-text\"><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong><strong>Assoc. Prof.Laddawan Senggunprai<\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/p>\n<\/div>\n<\/div>\n\n<\/div>\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:10%\"><\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:90%\">\n<p><strong>\u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22 (\u0e22\u0e49\u0e2d\u0e19\u0e2b\u0e25\u0e31\u0e07 5 \u0e1b\u0e35 2019-2023)<\/strong><\/p>\n\n\n\n<p><strong>\u0e19\u0e32\u0e19\u0e32\u0e0a\u0e32\u0e15\u0e34<\/strong><\/p>\n\n\n\n<p>1. Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, S<strong>enggunprai L<\/strong>, Prawan A, Kongpetch S. FGF10\/FGFR2 Signaling: Therapeutically Targetable Vulnerability in Ligand-responsive Cholangiocarcinoma Cells. In Vivo. 2023 Jul-Aug;37(4):1628-1637.<\/p>\n\n\n\n<p>2. Singdam P, Naowaboot J, <strong>Senggunprai L<\/strong>, Boonloh K, Hipkaeo W, Pannangpetch P. The Mechanisms of Neochlorogenic Acid (3-Caffeoylquinic Acid) in Improving glucose and Lipid Metabolism in Rats with Insulin Resistance Induced by A High Fat-High Fructose Diet. Trends in Sciences. 2023 Mar 1; 20(3): 6455.<\/p>\n\n\n\n<p>3. Malikrong P, Prawan A,Kongpetch S, <strong>Senggunprai L<\/strong>. Momordin ic triggers mitochondria-mediated apoptosis of cholangiocarcinoma cells and enhances the efficacy of conventional chemotherapeutic drugs. Farmacia. 2023 Feb;71(3):518\u2013525.<\/p>\n\n\n\n<p>4. Butsri S, Kukongviriyapan V, <strong>Senggunprai L<\/strong>, Kongpetch S, Prawan A. 13\u2011cis\u2011retinoic acid inhibits the self\u2011renewal, migration, invasion and adhesion of cholangiocarcinoma cells. Int J Mol Med 2023; 51. Published online 2023 Jan 21.<\/p>\n\n\n\n<p>5. Buranrat B, <strong>Senggunprai L<\/strong>, Prawan A, Kukongviriyapan V. Piperine Induces Cell Death, Apoptosis and Inhibits Migration in Cholangiocarcinoma Cells. Indian Journal of Pharmaceutical Education and Research. 2023 Jan-Mar; 57(1):161-166.<\/p>\n\n\n\n<p>6. Kaewmeesri P, Pocasap P, Kukongviriyapan V, Prawan A, Kongpetch S, <strong>Senggunprai L<\/strong>. Anti-metastatic Potential of Natural Triterpenoid Cucurbitacin B Against Cholangiocarcinoma Cells by Targeting Src Protein. Integr Cancer Ther. 2022 Jan-Dec;21:15347354221124861.<\/p>\n\n\n\n<p>7. Thongrung R, <strong>Senggunprai L<\/strong>, Hipkaeo W, Tangsucharit P, Pannangpetch P. Anti-angiogenesis and anti-inflammatory effects of Moringa oleifera leaf extract in the early stages of streptozotocin-induced diabetic nephropathy in rats. Asian Pacific Journal of Tropical Biomedicine. 2022 Jul 20;12(7):290-299.<\/p>\n\n\n\n<p>8<strong>. <\/strong><strong>Senggunprai L<\/strong>, Kukongviriyapan V, Prawan A, Kongpetch S. Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells. J Pharm Pharmacol . 2022 Jul 15;74(7):996-1005.<\/p>\n\n\n\n<p>9. Butsri S, Kukongviriyapan V, <strong>Senggunprai L<\/strong>, Kongpetch S, Prawan A. All-trans-retinoic acid induces RARB-dependent apoptosis via ROS induction and enhances cisplatin sensitivity by NRF2 downregulation in cholangiocarcinoma cells. Oncol Lett. 2022 Jun;23(6):179.<\/p>\n\n\n\n<p>10. Jaidee R, Kukongviriyapan V, <strong>Senggunprai L<\/strong>, Prawan A, Jusakul A, Laphanuwat P, Kongpetch S. Inhibition of FGFR2 enhances chemosensitivity to gemcitabine in cholangiocarcinoma through the AKT\/mTOR and EMT signaling pathways. Life Sci. 2022 May 1; 296: 120427.<\/p>\n\n\n\n<p>11. Buranrat B, <strong>Senggunprai L<\/strong>, Prawan A, Kukongviriyapan V. Effects of Simvastatin in Combination with Anticancer Drugs on Proliferation and Migration in Cholangiocarcinoma Cells. Indian J Pharm Sci 2022 Jan 17;84(1):72-79.<\/p>\n\n\n\n<p>12. Laphanuwat P, Kongpetch S, <strong>Senggunprai L<\/strong>, Prawan A, Kukongviriyapan V. Licochalcone A Induces Cholangiocarcinoma Cell Death Via Suppression of Nrf2 and NF-kappaB Signaling Pathways. Asian Pac J Cancer Prev. 2022 Jan 1; 23: 115-123.<\/p>\n\n\n\n<p>13. Wandee J, Srinontong P, Prawan A, <strong>Senggunprai L<\/strong>, Kongpetch S, Yenjai C, Kukongviriyapan V. Derrischalcone suppresses cholangiocarcinoma cells through targeting ROS-mediated mitochondrial cell death, Akt\/mTOR, and FAK pathways. Naunyn Schmiedebergs Arch Pharmacol. 2021 Sep;394(9):1929-1940.<\/p>\n\n\n\n<p>14. Phusrisom S, <strong>Senggunprai L<\/strong>, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Siriamornpun S, Chumroenphat T, Changsri R, Kukongviriyapan V. Anti-tumor activity of rice bran hydrolysates on migration, invasion and angiogenesis. Asian Pacific Journal of Tropical Biomedicine. 2021 Jul 1; 11(7): 317-3261.<\/p>\n\n\n\n<p>15. Kaewmeesri P, Kukongviriyapan V, Prawan A, Kongpetch S, <strong>Senggunprai L<\/strong>. Cucurbitacin B Diminishes Metastatic Behavior of Cholangiocarcinoma Cells by Suppressing Focal Adhesion Kinase. Asian Pac J Cancer Prev. 2021 Jan 1;22(1):219-225.<\/p>\n\n\n\n<p>16. Klungsaeng S, Kukongviriyapan V, Prawan A, Kongpetch S, <strong>Senggunprai L<\/strong>. Targeted modulation of FAK\/PI3K\/PDK1\/AKT and FAK\/p53 pathways by cucurbitacin B for the antiproliferation effect against human cholangiocarcinoma cells. American Journal of Chinese Medicine. 2020 Sep 9; 48(6): 1475-1489.<\/p>\n\n\n\n<p>17. Phusrisom S, <strong>Senggunprai L<\/strong>, Prawan A, Kongpetch S, Kukongviriyapan U, Thawornchinsombut S, Changsri R, Kukongviriyapan V. Rice bran hydrolysates induce immunomodulatory effects by suppression of chemotaxis, and modulation of cytokine release and cell-mediated cytotoxicity. Asian Pac J Trop Biomed 2020 Aug 17;10:470-8.<\/p>\n\n\n\n<p>18. Jaidee R, Kongpetch S, <strong>Senggunprai L<\/strong>, Prawan A, Kukongviriyapan U, Kukongviriyapan V. Phenformin inhibits proliferation, invasion, and angiogenesis of cholangiocarcinoma cells via AMPK-mTOR and HIF-1A pathways. Naunyn Schmiedebergs Arch Pharmacol. 2020 May 7.<\/p>\n\n\n\n<p>19. Buranrat B, Prawan A, <strong>Senggunprai L<\/strong>, Kukongviriyapan V. Inhibition of Growth and Migration of Cholangiocarcinoma Cells by Pamidronate. Experimental and Therapeutic Medicine. 2019 Nov; 18(5): 3977-3983.<\/p>\n\n\n\n<p>20. Somparn N, Prawan A, <strong>Senggunprai L<\/strong>, Kukongviriyapan U, Jetsrisuparb A, Lee MH, Kim DH, Kukongviriyapan V, Surh YJ. Cellular adaptation mediated through Nrf2-induced glutamate cysteine ligase up-regulation against oxidative stress caused by iron overload in \u03b2-thalassemia\/HbE patients. Free Radic Res. 2019 Jul;53(7):791-799.<\/p>\n\n\n\n<p>21. Buranrat B, Prawan A, <strong>Senggunprai L<\/strong>, Kukongviriyapan V. Alendronate blocks human cholangiocarcinoma cell proliferation and migration. Tropical Journal of Pharmaceutical Research 2019 Jun;18(6):1179-1184.<\/p>\n\n\n\n<p>22. Tusskorn O, Khunluck T, Prawan A, <strong>Senggunprai L<\/strong>, Kukongviriyapan V. Mitochondrial division inhibitor-1 potentiates cisplatin-induced apoptosis via the mitochondrial death pathway in cholangiocarcinoma cells. Biomed Pharmacother. 2019 Mar;111:109-118.<\/p>\n\n\n\n<p>23. Klungsaeng S, Kukongviriyapan V, Prawan A, Kongpetch S, <strong>Senggunprai L<\/strong>. Cucurbitacin B induces mitochondrial-mediated apoptosis pathway in cholangiocarcinoma cells via suppressing focal adhesion kinase signaling. Naunyn Schmiedebergs Arch Pharmacol. 2019 Mar;392(3):271-278.<\/p>\n\n\n\n<p>24. Wandee J, Prawan A, <strong>Senggunprai L<\/strong>, Kongpetch S, Kukongviriyapan V. Metformin sensitizes cholangiocarcinoma cell to cisplatin-induced cytotoxicity through oxidative stress mediated mitochondrial pathway. Life Sci. 2019 Jan 15;217:155-163.<\/p>\n\n\n\n<p>25. Khunluck T, Kukongviriyapan V, <strong>Senggunprai L<\/strong>, Duangarsong W, Prawan A. The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells. Integr Cancer Ther. 2019 Jan-Dec;18:1534735418820444.<\/p>\n\n\n\n<p>26. Tuponchai P, Kukongviriyapan V, Prawan A, Kongpetch S, <strong>Senggunprai L<\/strong>. Myricetin ameliorates cytokine-induced migration and invasion of cholangiocarcinoma cells via suppression of STAT3 pathway. J Cancer Res Ther. 2019 Jan-Mar;15(1):157-163.<\/p>\n\n\n\n<p>27. Ponglong J, <strong>Senggunprai L<\/strong>, Tangsucharit P, Changsri R, Proongkhong T, Pannangpetch P. Ethanolic extract of Tubtim-Chumphae rice bran decreases insulin resistance and intrahepatic fat accumulation in high-fat-high-fructose diet fed rats. Asian journal of pharmaceutical and clinical research. 2019 Jan;12(1):506-511.<\/p>\n\n\n\n<p><strong>\u0e23\u0e30\u0e14\u0e31\u0e1a\u0e0a\u0e32\u0e15\u0e34<\/strong><\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Kaewmeesri P, <strong>Senggunprai L<\/strong>. Cancer Metastasis and Target for Treatment. Srinagarind Medical Journal. 2019 Apr;34(2):211-6.<\/li>\n<\/ol>\n\n\n\n<p>2. Klungsaeng S, <strong>Senggunprai L<\/strong>. Protein Serine-Threonine Kinases as Drug Target In Cancer Treatment. Srinagarind Med J. 2020 Jul-Aug; 35(4): 488-495.<\/p>\n\n\n\n<p>3. Jaidee R, Kongpetch S, Prawan A, <strong>Senggunprai L<\/strong>, Kukongviriyapan U, Kukongviriyapan V. Quercetin Enhances Phenformin in Inhibition of Cholangiocarcinoma Cell Growth. Srinagarind Med J. 2563 May-Jun;35(3):249-254.<\/p>\n<\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\"><\/div>\n<\/div>\n\n<\/div>\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Assoc. Prof.Laddawan Senggunprai \u0e07\u0e32\u0e19\u0e27\u0e34\u0e08\u0e31\u0e22 (\u0e22\u0e49\u0e2d\u0e19\u0e2b\u0e25\u0e31\u0e07 5 \u0e1b\u0e35 2019-2023) \u0e19\u0e32\u0e19\u0e32\u0e0a\u0e32\u0e15\u0e34 1. Oeurn K, Jusakul A, Jaidee R, Kukongviriyapan V, Senggunprai L, Prawan A, Kongpetch S. FGF10\/FGFR2 Signaling: Therapeutically Targetable Vulnerability in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":38070,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_eb_attr":"","_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[62],"tags":[28],"class_list":["post-38069","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-personal","tag-pharmacology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Assoc. 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