งานวิจัย (ย้อนหลัง 5 ปี 2019-2023)

นานาชาติ

1. Kategeaw W, Nakkam N, Kiertiburanakul S, Sukasem C, Tassaneeyakul W, Chaiyakunapruk N. Cost-effectiveness analysis of HLA-B*13:01 screening for the prevention of co-trimoxazole-induced severe cutaneous adverse reactions among HIV-infected patients in Thailand. J Med Econ. 2023 Oct 13:1-17. doi: 10.1080/13696998.2023.2270868. Online ahead of print.

2. Wattanachai P, Amornpinyo W, Konyoung P, Purimart D, Khunarkornsiri U, Pattanacheewapull O, Tassaneeyakul W, Nakkam N. Association between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactions. Front Pharmacol. 2023 Sep 19;14:1248386. doi: 10.3389/fphar.2023.1248386. eCollection 2023.

3. Nakkam N, Saksit N, Konyoung P, Amornpinyo W, Khunarkornsiri U, Purimart D, Pattanacheewapull O, Naewla T, Wattanachai P, Khaeso K, Chumworathayi P, Tassaneeyakul W. Associations of HLA and drug-metabolizing enzyme genes in co-trimoxazole-induced severe cutaneous adverse reactions. Drug Metab Pharmacokinet. 2022 Oct 18;47:100480.

4. Chomean S, Nakkam N, Tassaneeyakul W, Attapong J, Kaset C. Development of label-free electrochemical impedance spectroscopy for the detection of HLA-B*15:02 and HLA-B*15:21 for the prevention of carbamazepine-induced Stevens-Johnson syndrome. Anal Biochem. 2022 Oct 1;658:114931. doi: 10.1016/j.ab.2022.114931. Epub ahead of print. PMID: 36191668.

5. Khaeso K, Komvilaisak P, Chainansamit SO, Nakkam N, Suwannaying K, Kuwatjanakul P, Hikino K, Dornsena A, Kanjanawart S, Laoaroon N, Vannaprasaht S, Taketani T, Tassaneeyakul W. NUDT15 is a key genetic factor for prediction of hematotoxicity in pediatric patients who received a standard low dosage regimen of 6-mercaptopurine. Drug Metabolism and Pharmacokinetics. 2022 Apr;43: 100436.

6. Nakkam N, Konyoung P, Amornpinyo W, Saksit N, Tiamkao S, Khunarkornsiri U, Khaeso K, Pattanacheewapull O, Jorns TP, Chumworathayi P, Tassaneeyakul W. Genetic variants associated with severe cutaneous adverse reactions induced by carbamazepine. Br J Clin Pharmacol. 2022 Feb;88(2):773-786. doi: 10.1111/bcp.15022. Epub 2021 Aug 28. PMID: 34350628.

7. Khaeso K, Udayachalerm S, Komvilaisak P, Chainansamit SO, Suwannaying K, Laoaroon N, Kuwatjanakul P, Nakkam N, Sukasem C, Puangpetch A, Tassaneeyakul W, Chaiyakunapruk N. Meta-Analysis of NUDT15 Genetic Polymorphism on Thiopurine-Induced Myelosuppression in Asian Populations. Front Pharmacol. 2021 Dec 2; 12: 784712.

8. Shotelersuk V, Wichadakul D, Ngamphiw C, Srichomthong C, Phokaew C, Wilantho A, Pakchuen S, Nakhonsri V, Shaw PJ, Wasitthankasem R, Piriyapongsa J, Wangkumhang P, Assawapitaksakul A, Chetruengchai W, Lapphra K, Khuninthong A, Makarawate P, Suphapeetiporn K, Mahasirimongkol S, Satproedprai N, Porntaveetus T, Pisitkun P, Praphanphoj V, Kantaputra P, Tassaneeyakul W, Tongsima S. The Thai reference exome (T-REx) variant database. Clin Genet. 2021 Dec;100(6):703-712. doi: 10.1111/cge.14060. Epub 2021 Sep 22.

9. Satapornpong P, Pratoomwun J, Rerknimitr P, Klaewsongkram J, Nakkam N, Rungrotmongkol T, Konyoung P, Saksit N, Mahakkanukrauh A, Amornpinyo W, Khunarkornsiri U, Tempark T, Wantavornprasert K, Jinda P, Koomdee N, Jantararoungtong T, Rerkpattanapipat T, Wang CW, Naisbitt D, Tassaneeyakul W, Ariyachaipanich M, Roonghiranwat T, Pirmohamed M, Chung WH, Sukasem C. HLA-B*13:01 Is a Predictive Marker of Dapsone-Induced Severe Cutaneous Adverse Reactions in Thai Patients. Front Immunol. 2021 May 4;12:661135.

10. Pratoomwun J, Thomson P, Jaruthamsophon K, Tiyasirichokchai R, Jinda P, Rerkpattanapipat T, Tassaneeyakul W, Nakkam N, Rerknimitr P, Klaewsongkram J, Srinoulprasert Y, Pirmohamed M, Naisbitt DJ, Sukasem C. Characterization of T-Cell Responses to SMX and SMX-NO in Co-Trimoxazole Hypersensitivity Patients Expressing HLA-B*13:01. Front Immunol. 2021 Apr 29;12:658593.

11. Khaeso K, Nakkam N, Komwilaisak P, Wongmast P, Chainansamit SO, Dornsena A, Kanjanawart S, Vannaprasaht S, Tassaneeyakul W. Genetic Polymorphisms of Drug-Metabolizing Enzymes Involved in 6-Mercaptopurine-Induced Myelosuppression in Thai Pediatric Acute Lymphoblastic Leukemia Patients. J Pediatr Genet. 2021 Mar;10(1):29-34.

12. Singto T, Tassaneeyakul W, Porasuphatana S. Protective effects of purple waxy corn on aflatoxin B1-induced oxidative stress and micronucleus in HepG2 cells. Indian Journal of Pharmaceutical Sciences. 2020 May-June; 82(3): 506-513.

13. Sukasem C, Pratoomwun J, Satapornpong P, Klaewsongkram J, Rerkpattanapipat T, Rerknimitr P, Lertpichitkul P, Puangpetch A, Nakkam N, Konyoung P, Khunarkornsiri U, Disphanurat W, Srisuttiyakorn C, Pattanacheewapull O, Kanjanawart S, Kongpan T, Chumworathayi P, Saksit N, Bruminhent J, Tassaneeyakul W, Chantratita W, Pirmohamed M, Thai Severe Cutaneous Adverse Drug Reaction research g. Genetic association of co-trimoxazole-induced severe cutaneous adverse reactions is phenotype-specific: HLA class I genotypes and haplotypes. Clin Pharmacol Ther. 2020 May 26.

14. Areesinpitak T, Kanjanawart S, Nakkam N, Tassaneeyakul W, Vannaphasaht S. Prevalence of CYP2C19, CYP3A4 and FMO3 genetic polymorphisms in healthy northeastern Thai volunteers. ScienceAsia. 2020 August;46(4): 397-402.

15. Pan RY, Chu MT, Wang CW, Lee YS, Lemonnier F, Michels AW, Schutte R, Ostrov DA, Chen CB, Phillips EJ, Mallal SA, Mockenhaupt M, Bellón T, Tassaneeyakul W, White KD, Roujeau JC, Chung WH, Hung SI. Identification of drug-specific public TCR driving severe cutaneous adverse reactions. Nat Commun. 2019 Aug 8;10(1):3569.

16. Leong SL, Chaiyakunapruk N, Tassaneeyakul W, Arunmanakul P, Nathisuwan S, Lee SWH. Roles of pharmacogenomics in non-anthracycline antineoplastic-induced cardiovascular toxicities: A systematic review and meta-analysis of genotypes effect. International Journal of Cardiology. 2019 Apr 1;280:190-197.

17. Su SC, Chen CB, Chang WC, Wang CW, Fan WL, Lu LY, Nakamura R, Saito Y, Ueta M, Kinoshita S, Sukasem C, Yampayon K, Kijsanayotin P, Nakkam N, Saksit N, Tassaneeyakul W, Aihara M, Lin YJ, Chang CJ, Wu T, Hung SI, Chung WH. HLA Alleles and CYP2C9*3 as Predictors of Phenytoin Hypersensitivity in East Asians. Clin Pharmacol Ther. 2019 Feb;105(2):476-485.

18. Boonsom S, Tassaneeyakul W, Wongratanacheewin S, Kaewraemruaen C, Vannaprasaht S. Long term stability of immunophenotypic T cell subsets from whole blood of tacrolimus-based therapy kidney transplantation patients and healthy volunteers by flow cytometric analysis. Asia-Pacific Journal of Science and Technology. 2019;24(3): Article number APST-24-03-09.

ระดับชาติ

1. Konyoung P, Nakkam N, Khawsuk H, Khaeso K, Tassaneeyakul W. Severe Cutaneous Adverse Drug Reactions: A Study of 216 Patients from Udon Thani Hospital. Thai J Pharmacol. 2020 Jun 22;42(1):5-19.

2. Kanyarat Khaeso, Nontaya Nakkam, Sirimas Kanjanawart, Suda Vannaprasaht, Patcharee Komvilaisak, Wichittra Tassaneeyakul. Pharmacogenetics of Thiopurine Drugs: Role of Thiopurine SMethyltransferase and Nucleoside Diphosphate-Linked Moiety X Motif 15 Genetic Polymorphisms on Drugs-induced Myelosuppression. Thai J Pharmacol 2019 June 13;41(No. 1):68-82.